| ORIGINAL ARTICLE: BIOLOGICAL ANTHROPOLOGY |
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| Year : 2021 | Volume
: 16
| Issue : 2 | Page : 106-114 |
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Prevalence of osteoporosis and its associated work-related factors and obesity among a sample of Egyptian women indoor workers and employees
Nayera E Hassan1, Sahar A El-Raufe El-Masry PhD 1, Walaa S Mahmoud1, Muhammad Al-Tohamy Soliman1, Aya Khalil1, Mahmoud A.S. Afify1, Manal M Aly1, Enas A Rasheed2, Gamila S.M. El-Saeed3, Khadija M Alian1
1 Department of Biological Anthropology, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt
2 Department of Clinical and Chemical Pathology, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt
3 Department of Medical Biochemistry, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt
Correspondence Address:
Sahar A El-Raufe El-Masry
Department of Biological Anthropology, National Research Centre, 33 El-Bohooth Street, Dokki, Giza, Cairo 12622
Egypt
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jasmr.jasmr_17_21
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Background/aim Obesity and osteoporosis are progressive diseases with complex etiology. They constitute a major public health concern nowadays. This study aimed to assess the prevalence of osteoporosis, vitamin D profile, and its relation to obesity, bone markers, and leptin among a sample of Egyptian women indoor workers and employees at the National Research Centre.
Patients and methods A cross-sectional study that included 116 Egyptian women aged 25–60 years. Anthropometric measurements (body weight, height, and BMI), dual-energy radiograph absorptiometry [bone mineral density (BMD) and its T score at both lumbar spines and neck of the femur], and laboratory investigations (leptin, calcium, vitamin D, and C-terminal peptide) were done for all participants. They were classified according to their BMI and BMD-T scores at lumbar spines and femur neck.
Results Osteoporosis was diagnosed among 11.2, 25.2, and 6.8% of participants using the BMD-T score at lumbar spines, femur neck, and at the two sites respectively; osteopenia was diagnosed among 44.8, 51.3, and 25%, respectively. Osteoporosis was significantly more frequent among normal weight women than overweight/obese ones. Normal weight osteoporotic women had significantly higher values of vitamin D and C-terminal peptide, and lower values of leptin and BMI than the nonosteoporotic ones. Among osteoporotic women, BMI had a significant negative correlation with vitamin D. BMI had significant positive correlations with BMD at both lumbar spines and femur neck and their T scores among nonosteoporotic women and total sample. BMI had a significant positive correlation with the C-terminal peptide among the osteoporotic, nonosteoporotic, and total sample, with leptin and age among the osteoporotic and total sample.
Conclusion BMI had a significant positive correlation with hypovitaminosis D, C-terminal peptide, leptin, and age. It had a significant positive correlation with BMD among nonosteoporotic women, but not among osteoporotic ones. Obesity protects from osteoporosis. Dual-energy radiograph absorptiometry at lumbar spines underestimate the diagnosis of osteoporosis and osteopenia.
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