Journal of The Arab Society for Medical Research

ORIGINAL ARTICLE
Year
: 2015  |  Volume : 10  |  Issue : 1  |  Page : 41--46

Impact of sperm cryopreservation on child sex after intracytoplasmic sperm injection


Ahmed M Omar1, Mahmoud F Abdel Hamid1, Amr H Abbassy2 
1 Department of Dermatology and Venerology, National Research Centre, Cairo, Egypt
2 Department of Obstetrics and Gynecology, National Research Centre, Cairo, Egypt

Correspondence Address:
Ahmed M Omar
Department of Dermatology and Venerology, National Research Centre, Dokki, PO Box 12622, Cairo
Egypt

Background/aim Sperm cryopreservation causes extensive damage to sperm membranes and its ultrastructural morphology, affecting the fertilization ability by decreasing the percentage of normal intact acrosomes and consequently the acrosine activity. This retrospective study aims at detecting the effect of sperm cryopreservation on the baby«SQ»s sex after intracytoplasmic sperm injection (ICSI) in terms of the susceptibility of X versus Y chromosome baring spermatozoa to cryopreservation. Patients and methods This retrospective study included 87 ICSI cycles performed with post-thawed spermatozoa. The patients were classified into two groups (I and II) according to the total sperm count before freezing. Results This study included 87 ICSI cycles performed with post-thawed spermatozoa. Patients were classified into two groups (I and II) according to the total sperm count before freezing. Group I included 43 patients with a sperm count less than 0.1 × 10 6 /sample (countable samples). Group II included 44 patients with a sperm count more than 0.1 × 10 6 /sample (uncountable samples). The numbers of fertilized M II, good embryos, clinical pregnancy, and male babies were significantly higher in group I compared with group II. Conclusion ICSI using post-thawed spermatozoa of countable samples yielded a higher male sex ratio (80.8%) compared with uncountable samples (28.6%). Thus, spermatozoa that successfully survived the freeze-thaw procedure exhibited an improved chromatin structure and nuclear maturity. These data suggest that sperm cryopreservation may improve the fertilization rate, enhance early embryo development parameters, as well as pregnancy outcome after ICSI.


How to cite this article:
Omar AM, Abdel Hamid MF, Abbassy AH. Impact of sperm cryopreservation on child sex after intracytoplasmic sperm injection.J Arab Soc Med Res 2015;10:41-46


How to cite this URL:
Omar AM, Abdel Hamid MF, Abbassy AH. Impact of sperm cryopreservation on child sex after intracytoplasmic sperm injection. J Arab Soc Med Res [serial online] 2015 [cited 2021 Oct 17 ];10:41-46
Available from: http://www.new.asmr.eg.net/article.asp?issn=1687-4293;year=2015;volume=10;issue=1;spage=41;epage=46;aulast=Omar;type=0