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  Indian J Med Microbiol
 

Figure 2: (a) A longitudinal section of the middle shaft of the femur of a rat treated with pilocarpine showing the resorption cavity (curved arrow) and decreased number of osteocytes (stars). The bone tissue contains calcified cartilage (C) and osteoporotic cavities (black arrow). (b) The head of the femur of a rat treated with pilocarpine showing a slight decrease in the thickness of the bone trabeculae (arrow). (c) A longitudinal section of the middle shaft of the femur of a pilocarpineinduced epileptic rat treated only with valproate, showing a marked decrease in shaft cortical width, erosion cavity at the outer surface (arrow), and decreased number of osteocytes. The bone tissue contains calcifi ed cartilage and resorption cavities (star). (d) The head of the femur of a pilocarpine-induced epileptic rat treated only with valproate showing a marked decrease in the thickness of the bone trabeculae (arrow). (a, c) Hematoxylin and eosin-stained sections; (b, d) binary image morphometric measurement, ×400.

Figure 2: (a) A longitudinal section of the middle shaft of the femur of a rat treated with pilocarpine showing the resorption cavity (curved arrow) and decreased number of osteocytes (stars). The bone tissue contains calcified cartilage (C) and osteoporotic cavities (black arrow). (b) The head of the femur of a rat treated with pilocarpine showing a slight decrease in the thickness of the bone trabeculae (arrow). (c) A longitudinal section of the middle shaft of the femur of a pilocarpineinduced epileptic rat treated only with valproate, showing a marked decrease in shaft cortical width, erosion cavity at the outer surface (arrow), and decreased number of osteocytes. The bone tissue contains calcifi ed cartilage and resorption cavities (star). (d) The head of the femur of a pilocarpine-induced epileptic rat treated only with valproate showing a marked decrease in the thickness of the bone trabeculae (arrow). (a, c) Hematoxylin and eosin-stained sections; (b, d) binary image morphometric measurement, ×400.