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  Indian J Med Microbiol
 

Figure 4: (a) A longitudinal section of the middle shaft of the femur of a pilocarpine-induced epileptic rat treated with valproate and fi sh liver oil showing increased mean thickness of the shaft compared with group treated only with valproate. There was an erosion cavity at the endosteal surface (arrow). A resorption cavity in bone tissue (star) was also observed. (b) The head of the femur of a rat of the same group showing increased thickness of the bone trabeculae (arrow) compared with the group of rats treated only with valproate. (c) A longitudinal section of the middle shaft of the femur of a pilocarpineinduced epileptic rat treated with valproate and propolis showing an increase in shaft cortical width, increased number of osteocytes (arrowhead) – that is, recovery of bone tissue. (d) The head of the femur of a rat of the same group showing a decrease in the mean area of the Haversian canal (arrows) compared with group treated only with valproate. (a, c) Hematoxylin and eosin-stained sections; (b, d) binary image morphometric measurement, ×400.

Figure 4: (a) A longitudinal section of the middle shaft of the femur of a pilocarpine-induced epileptic rat treated with valproate and fi sh liver oil showing increased mean thickness of the shaft compared with group treated only with valproate. There was an erosion cavity at the endosteal surface (arrow). A resorption cavity in bone tissue (star) was also observed. (b) The head of the femur of a rat of the same group showing increased thickness of the bone trabeculae (arrow) compared with the group of rats treated only with valproate. (c) A longitudinal section of the middle shaft of the femur of a pilocarpineinduced epileptic rat treated with valproate and propolis showing an increase in shaft cortical width, increased number of osteocytes (arrowhead) – that is, recovery of bone tissue. (d) The head of the femur of a rat of the same group showing a decrease in the mean area of the Haversian canal (arrows) compared with group treated only with valproate. (a, c) Hematoxylin and eosin-stained sections; (b, d) binary image morphometric measurement, ×400.