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  Indian J Med Microbiol
 

Figure 1 Photomicrographs of cerebral cortex sections stained by hematoxylin–eosin stain (a). Control group showing normal neuronal cells with prominent nuclei (N). (b) Dexamethasone group showing necrosis of neurons, vacuoles (V), and apoptotic (arrowhead) and pyknotic nuclei (P). Focal gliosis (arrow) and red neurons (R). (c) Dexamethasone and Hypericum perforatum (100 mg/kg) group showing vacuoles (V), apoptotic (arrowhead) and pyknotic nuclei (P), and red neurons (R). (d) Dexamethasone and H. perforatum (200 mg/kg) group showing some apoptotic (arrowhead) and pyknotic nuclei (P) and red neurons (hematoxylin–eosin stain, ×400).

Figure 1 Photomicrographs of cerebral cortex sections stained by hematoxylin–eosin stain (a). Control group showing normal neuronal cells with prominent nuclei (N). (b) Dexamethasone group showing necrosis of neurons, vacuoles (V), and apoptotic (arrowhead) and pyknotic nuclei (P). Focal gliosis (arrow) and red neurons (R). (c) Dexamethasone and <i>Hypericum perforatum</i> (100 mg/kg) group showing vacuoles (V), apoptotic (arrowhead) and pyknotic nuclei (P), and red neurons (R). (d) Dexamethasone and <i>H. perforatum</i> (200 mg/kg) group showing some apoptotic (arrowhead) and pyknotic nuclei (P) and red neurons (hematoxylin–eosin stain, ×400).