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Figure 2 Photomicrographs of striatum sections stained by hematoxylin–eosin stain. (a) Control group shows normal neuronal cells with prominent nuclei (N). (b) Dexamethasone group shows degenerated, necrosis of neurons, vacuoles (V), apoptotic (arrowhead) and pyknotic nuclei (P), and dilated blood vessel (thin arrow). (c) Dexamethasone and Hypericum perforatum (100 mg/kg) group shows necrosis of some neurons, vacuoles (V), apoptotic (arrowhead) and pyknotic nuclei (P), and red neurons. (d) Dexamethasone and H. perforatum (200 mg/kg) group shows some apoptotic (arrowhead) and pyknotic nuclei (P) and red neurons (hematoxylin–eosin stain, ×400). |
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